美洲水貂TYR基因变异与毛色相关性分析∗

摘要

This study aimed to discuss the effects of mutations of TYR gene sequence in mink on mink coat color. TYR exon 1 sequence of white mink, silver blue mink and American short⁃hair mink was amplified. The results showed that a mutation site T78A transversion was significantly cor⁃related with white mink coat color ( P<0�000 1 ) . The gene phylogenetic of TYR gene in different species was also analyzed, with the purpose of providing reference for researches on mink TYR gene system development and selective breeding of mink coat color.%为探讨不同毛色水貂酪氨酸酶基因（ TYR）编码区序列变异对水貂毛色的影响，对红眼白貂、美国短毛黑水貂、银蓝水貂TYR外显子1进行序列扩增分析，结果找到1个突变位点c．78A＞T颠换与白色水貂毛色关联极显著（ P＜0�0001）。文章还对不同物种TYR基因部分序列进行遗传进化分析，以期对水貂TYR基因系统发育研究和水貂毛色的选种选育提供依据。