Objective To explore the clinical characteristics of hyperdense cerebral artery sign ,evaluate the safety and efficacy of hyperdense cerebral artery sign treated with intravenous thrombolysis. Methods Retrospectively analyzed the clinical data and follow-up results of 15 cases that were found out having hyperdense cerebral artery sign with CT and having neurological deficit symptoms ,and the 15 cases were treated with intravenous thrombolysis. Among the 15 cases ,5 were treated with urokinase and 10 were treated with alteplase(rt-PA). Results After thrombolysis ,re-examined with CT ,CTA and MRA angiography followed up in 7 cases ,DSA angiography followed up in 4 cases ,follow-up time was 3 to 18 months ,average 10.4 months. The clinical symptoms of all the patients are different degree im⁃proved ,there were not infarction and hemorrhage happened again. Conclusion The hyperdense cerebral artery sign treated with intravenous thrombolytic therapy can improve the clinical symptoms ,and the safety is good.%目的：探讨脑动脉高密度征的临床特点，评价脑动脉高密度征行静脉溶栓的安全性及有效性。方法回顾性分析15例入院前行头部CT发现脑动脉高密度征后且有神经缺失症状患者行静脉溶栓病例的临床资料及随访结果。其中采用尿激酶5例，阿普替酶（rt-PA）10例。结果溶栓后复查CT、CTA及MRA造影随访7例，DSA造影随访4例，随访时间3～18个月，平均10.4个月。所有患者临床症状均得到不同程度的改善，并未再次发生梗死或出血。结论脑动脉高密度征行静脉溶栓可改善临床症状，且安全性好。
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