恶性梗阻性黄疸一经发现多已失去外科手术的机会，经皮经肝胆道引流术（PTBD）或内支架植入能引流淤滞胆汁从而能较好地改善患者临床症状，却未能针对肿瘤加以治疗，从而不能明显延长患者的生存期。内支架植入联合放疗、动脉灌注化疗、支架内射频消融等双介入治疗方式能在解决患者黄疸症状的同时处理肿瘤问题，是更为理想的治疗方式。现就内支架植入术联合放疗、动脉灌注化疗及支架内射频消融的应用及其治疗效果作一综述。%Usually, the patient has already lost the opportunity to receive surgical treatment once the malignant obstructive jaundice is diagnosed. Although percutaneous transhepatic biliary drainage (PTBD) or inner-stent implantation can improve the patient’s clinical symptoms, the tumor itself actually gets no any treatment from PTBD, thus the patient’s survival time can not be significantly prolonged. By using dual interventional therapy, such as inner-stent implantation combined with radioactive seed implantation, or with arterial infusion chemotherapy, or with intra- stent radiofrequency ablation, both the clinical jaundice symptoms and the tumor itself can be treated. Therefore, dual interventional technique is a more ideal means for the treatment of malignant obstructive jaundice. This paper aims to make a brief review about the application and the therapeutic effect of inner - stent implantation combined with radioactive seed implantation, arterial infusion chemotherapy or intra-stent radiofrequency ablation, etc. in treating malignant obstructive jaundice.(J Intervent Radiol, 2014, 23:360-364).
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