溶胶-凝胶法制备不同形态的半透明羟基磷灰石陶瓷

摘要

In order to fabricate translucent hydroxyapatite ceramics with different forms,using micro-sized HA powders as the raw material and chitin as adhesive,the ceramic green was prepared by Sol-Gel method.Subsequently,pure HA ceramics were obtained by normal pressure sintering.Translucent HA ceramics were then fabricated via hot isostatic pressing (HIP) sintering.The Sol-Gel method is easy to obtain shaped ceramic products.The so-produced HA ceramic spheres with a good sphericity and the HA ceramic fibers with a high aspect ratio have the density of 99.1％ and the average grain size of 2.2 μm.Compressive strength of translucent HA ceramic spheres is 10.2 MPa whith It is higher than that of conventionally-sintered dense and porous HA ceramic spheres (8.9 and 4.7 MPa,respectively).Results of biomimetic mineralization and cell culture show that translucent HA ceramics have good biocompatibility.%为探索制备不同形态半透明羟基磷灰石(T-HA)陶瓷的方法,采用微米级HA粉体为原料,甲壳素为粘结剂,用溶胶-凝胶法制备出球状和纤维状的陶瓷初坯,然后进行常压烧结得到纯HA陶瓷,最后经过热等静压烧结得到T-HA陶瓷.溶胶-凝胶法赋形简单,制备出的球状T-HA陶瓷的球形度良好,纤维状T-HA陶瓷的纵横比高,其致密度为99.1％,平均晶粒尺寸为2.2 μm.其中球状半透明HA陶瓷的抗压强度为10.2 MPa,高于常规烧结得到的球状致密和多子孔 HA陶瓷(分别为8.9和4.7 MPa).仿生矿化和细胞培养的结果显示半透明HA陶瓷具有良好的生物相容性.