刺蓝抗疲口服液对小鼠免疫及抗应激作用的影响

摘要

目的 研究刺蓝抗疲口服液的抗应激作用及对免疫功能的影响.方法 将小鼠分为6组:空白组,模型组,口服养生精组,刺蓝抗疲口服液低、中、南剂量组,采用小鼠注射环磷酰胺和腹部手术分别建立免疫抑制和创伤模型,现察刺蓝抗疲口服液对免疫低下小鼠碳粒廓清、血清溶血素、创伤小鼠负重游泳耗竭时间和常压耐缺氧存活时间的影响.结果 与模型组比较,刺蓝抗疲口服液高剂组碳粒廓清指数、血清溶血素明显提高,差异有统计学意义(P＜0.01)；小鼠负重游泳时间和耐缺氧的生存时闻明显延长,差异有统计学意义(P＜0.05,P＜0.01).结论 刺蓝抗疲口服液具有抗应激和增强小鼠非特异性免疫及体液免疫功能的作用.%Objective To study the effect of Cilan Kangpi oral liquid on anti-stress and the influence in immune function.Methods Immuno-suppressed model were established by intraperi-toneal injecting of cyclophosphamide and abdominal trauma model were established by surgery.Then,the effects of Cilan Kangpi oral liquid on carbon clearance and serum hemolysin in low immune mice,load swimming time and the anti-hypoxia survival time of wound mice were observed.Results Compared with the modeling group,carbon clearance index and serum hemolysin were significantly improved and the load swimming time and anti-hypoxia survival time were significantly prolonged in Cilan Kangpi oral liquid high-dose group (all P<0.01).Conclusion Cilan Kangpi oral liquid can enhance the anti-stress ability and improve non-specific immune and humoral immune function in mice.