目的:研究血浆脂联素水平及血清肿瘤坏死因子-α含量与非酒精性脂肪肝的相关性,探讨腹部推拿对非酒精性脂肪肝病患者脂联素水平及肿瘤坏死因子-α含量的影响.方法:选择非酒精性脂肪肝患者97例作为研究对象,按随机数字表法随机分为治疗组与对照组.对照组患者在饮食、运动指导的基础上,加用水飞蓟宾葡甲胺片 200 mg口服,每日3次,疗程共 30 d.治疗组在饮食、运动指导的基础上,加用腹部推拿1次/d,疗程共 30 d.治疗前后测定血浆脂联素水平及血清肿瘤坏死因子-α含量.结果:与对照组相比,治疗组血浆脂联素水平升高明显,两组比较差异有显著性(P<0.05);与对照组相比,治疗组血清肿瘤坏死因子-α含量下降明显,两组比较差异有显著性(P<0.05);结论:腹部推拿治疗非酒精性脂肪肝病有效,可能是通过升高血浆脂联素、降低血清肿瘤坏死因子-α含量实现的.%Objective: to study the relationship of plasma adiponectin level and TNF-α and nonalcoholic fatty liver, and to discuss the effect of Tuina on abdomen on adiponectin and TNF-αcontent. Methods: 97 cases with nonalcoholic fatty liver were divided into treatment group and control group by random digits table. On the basis of diet and exercise instructions, control group were administered with silybin meglumine 200mg, three times a day for 30 days as a course, while treatment group were given Tuina on abdomen once a day for 30 days as a course. Determine the plasma adiponectin level and TNF-acontent before and after the treatment. Results: Compared to control group, adiponectin level of treatment group increased with significant difference ( P < 0. 05 ), and TNF-acontent decreased with significant difference ( P < 0. 05 ). Conclusion: Tuina on abdomen is effective in treatment of nonalcoholic fatty liver by way of heightening adiponectin level and lowering TNF-α content.
展开▼
