眼睑型汗管瘤电解治疗的临床疗效及复发的影响因素

摘要

目的:探讨电解治疗对眼睑型汗管瘤的临床疗效及复发的影响因素.方法:95例采用EIS-A型电解美容仪治疗的眼睑型汗管瘤患者分为青年组(n=48)和中老年组(n=47),每3周治疗1次,皮疹消退80％或以上为治疗终点;比较每次治疗后的创面愈合时间、红肿消退时间、治疗时疼痛感受(VAS)评分,统计治疗完全结束时两组的治疗次数及比较治疗结束3周时的治疗效果;对治疗后3年内复发与未复发患者的年龄、性别、疗后创面愈合时间、红肿消退时间及VAS评分,进行多因素Logistic回归分析探讨眼睑型汗管瘤复发的影响因素.结果:95例汗管瘤患者治疗完成3周时的总有效率达97.9％,随访3年时复发率28.4％,未出现疗后色素沉着、色素减退和瘢痕患者;青年组(100％)和中老年组(95.7％)临床疗效相当(P=0.693),两年龄组每次治疗后的愈合时间、红肿消退时间、VAS评分及治疗后3年内的复发率比较,差异均无统计学意义(P>0.05);总治疗次数在非复发组高于复发组(P<0.0l),多因素Logistic回归分析结果显示,治疗次数是眼睑型汗管瘤复发的保护性因素(OR=0.322,P<0.0l).结论:电解治疗眼睑型汗管瘤根除率高、复发少、副作用轻微,治疗次数是复发的保护性因素.%Objective: To investigate the effect of electrotherapy on eyelid type syringom. Methods： 95 cases of eyelid type syringoma treated with EIS-A type electrolysis beauty instrument were divided into two groups: young group(n= 48) and middle and old group(n=47). The patients were treated once every 3 weeks, and 80％ or more of the exanthema disappeared as the end point of treatment. The healing time of wound, the time of redness and swelling regression, the(VAS) score of pain perception during treatment, the times of treatment at the end of treatment and the effect of treatment at the end of 3 weeks were compared between the two groups. The age, sex, wound healing time, redness time and VAS score of patients with or without recurrence within 3 years after treatment were studied by multivariate Logistic regression analysis. Results: The total effective rate of 95 patients with syringoma was 97.9％ at the end of 3 weeks, and the recurrence rate was 28.4％ after 3 years follow-up without pigmentation, hypopigmentation and scar after treatment. The clinical efficacy of the young group(100％) and the middle-aged group(95.7％) was equal（P=0.693）. The healing time, redness extinction time, and VAS score and recurrence rate within 3 years were compared after treatment in two groups, and the difference was not statistically significant(P＞0.05). The total treatment times in non-recurrence group were higher than that in recurrent group(P＜0.01). The multivariate Logistic regression analysis showed that the treatment frequency was a protective factor for the recurrence of eyelid syringom（a OR=0.322, P＜0.0l）. Conclusion:The eradication rate of eyelid type syringoma is high, the recurrence is less, the side effect is slight, and the times of treatment is the protective factor of recurrence.