早期胃癌患者的循证治疗

摘要

Objective To formulate an evidence-based treatment plan for a patient with early gastric cancer.Methods Based on the clinical questions raised by a patient with early gastric cancer, we searched the Cochrane Library (online year 2000 to 2009), PubMed and EMBASE (year 2000 to 2009) for meta-analysis, systematic review,randomized controlled trial (RCT), guideline, case-control studies. Results We found 14 practice guidelines or systematic reviews or meta analysis, 5 RCT, and 7 case-control studies. After analyzing those papers and sought the opinion of the patient, we founded a proper treatment protocol for the patient. Conclusion Survival rate and therapeutic efficacy could be improved through evidence-based treatment.%目的 借助循证医学的方法为1例早期胃癌患者确定治疗目标及治疗方案.方法 在充分评估患者情况后,提出临床问题,从Cochrane图书馆(网络版2000-2009年)、PubMed和EMBASE(2000-2009年)上进行检索.检索的主题词为:stomach cancer,early cancer,therapy,preoperative treatment,postoperative treatment,lymph node metastasis,invasive therapeutic technique,postoperative complication,postoperative hemorrhage,meta analysis,systematic review,randomized controlled trial (RCT),practice guideline.结果 共检出与不同问题相关的指南、系统评价或Meta分析14篇,随机对照试验5篇,非随机对照研究7篇.通过对检索结果进行分析,结合患者意愿,为患者制定了合理的治疗方案.结论 采用循证治疗的方法,为1位诊断为早期胃癌患者确定合理的治疗方案,可以有效提高治疗效果,提高患者生存质量.