首页> 中文期刊> 《心电与循环》 >老年急性冠脉综合征患者尿微量白蛋白/尿肌酐比值与PCI后恶性室性心律失常的相关性分析

老年急性冠脉综合征患者尿微量白蛋白/尿肌酐比值与PCI后恶性室性心律失常的相关性分析

         

摘要

Objective To investigate the correlation between urine albumin/creatinine ratio (UACR) and malignant ventricular arrhythmia (MVA) in elderly patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI).Methods A total of 188 elderly ACS patients underwent PCI were enrolled and divided into increased UACR group (UACR>30 mg/g, n=60 cases) and normal UACR group (UACR≤30 mg/g, n=128 cases) according to UACR level at admission. The incidence of MVA was compared between the two groups. Logistic regression equation was used to analyze the relationship between UACR and MVA. Results The incidence of MVA was significantly higher in increased UACR group than in normal UACR group (25.00% vs11.72%, χ2=5.373, P<0.05). UACR level was significantly higher in patients with MVA [ (24.53±9.65) mg/g] than without MVA[ (18.76 ±5.24) mg/g] (t=4.882, P <0.01). Multivariate Logistic regression equation showed that UACR was an independent risk factor of MVA in elderly ACS patients (OR= 2.753, 95%CI:2.454-11.732, P<0.01). Conclusion The risk of MVA increases in elderly ACS patients with increased UACR after PCI.%目的 探讨老年急性冠脉综合征(ACS)患者尿微量白蛋白/尿肌酐比值(UACR)与经皮冠状动脉介入治疗(PCI)后恶性室性心律失常(MVA)的相关性.方法 选取2016年2月至2018年2月老年ACS患者188例为研究对象,按照入院时UACR水平分为UACR增高组(UACR>30mg/g)60例和UACR正常组(UACR≤30mg/g)128例.比较两组MVA发生率;采用log is tic回归方程分析UACR与MVA的关系.结果 UACR增高组MVA发生率显著高于UACR正常组(25.00%vs 11.72%,χ2=5.373,P<0.05).MVA患者UACR水平[(24.53±9.65)mg/g]显著高于非MVA患者[(18.76±5.24)mg/g],差异有统计学意义(t=4.882,P<0.01).多因素log is tic回归方程显示UACR是老年ACS患者发生MVA的独立危险因素(OR=2.753,95%CI:2.454~11.732,P<0.01).结论 UACR增高的老年ACS患者PCI后MVA的发生风险增加.

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