首页> 外国专利> Natriuretic peptide / troponin ratio for the assessment of myocardial dysfunction existing in patients with acute coronary syndromes

Natriuretic peptide / troponin ratio for the assessment of myocardial dysfunction existing in patients with acute coronary syndromes

机译:利钠肽/肌钙蛋白比值评估急性冠脉综合征患者存在的心肌功能障碍

摘要

The present invention relates to methods and devices for clinical diagnostics. More specifically, relates to a method of diagnosing subjects suffering from acute myocardial infarction whether they are also suffering myocardial dysfunction, the existing method, the present invention, a sample of (a) said subject step (d); step of calculating (c) ratio (natriuretic peptide / cardiac troponin); determining the amount of a cardiac troponin in a sample of (b) said subject; measuring the amount of a natriuretic peptide and a step of diagnosing elevated levels natriuretic peptide level based on the ratio calculated in (c), elevated, or associated with myocardial dysfunction existing or is caused by acute myocardial infarction. The method makes it possible to determine myocardial dysfunction, individual, whether affected with heart failure, especially before the myocardial infarction occurs. The invention further relates to a diagnostic device and a kit for performing the method described above. None [Selection Figure]
机译:本发明涉及用于临床诊断的方法和设备。更具体而言,涉及一种诊断患有急性心肌梗塞的受试者是否也患有心肌功能障碍的方法,现有方法,本发明,(a)所述受试者步骤(d)的样品;计算(c)比率(利钠肽/心肌肌钙蛋白)的步骤;确定(b)所述受试者的样品中的心脏肌钙蛋白的量;测量利钠肽的量,并根据(c)中计算的比率,升高的或与急性心肌梗死或与之相关的心肌功能障碍,诊断利钠肽水平升高的步骤。该方法使得可以确定个体是否患有心力衰竭,特别是在心肌梗塞发生之前,是否患有心力衰竭。本发明还涉及用于执行上述方法的诊断设备和套件。无[选择图]

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