隐匿性乳腺癌多以同侧腋窝淋巴结肿大为首发症状，临床少见，诊断是其难点。诊断过程建议先行肿大淋巴结空芯针穿刺，并加做免疫组化，如支持乳腺癌转移，同时排除其他部位原发肿瘤后可确诊。治疗以全乳切除加腋窝淋巴结清扫术为标准，新辅助化疗是影响其预后的独立因素，术前推荐先行新辅助化疗，术后根据免疫组化结果，辅以化疗、放疗、内分泌治疗等。隐匿性乳腺癌的预后与同期其他类型的乳腺癌相似。%Occult breast cancer is a rare disease with the primary symptom of enlarged ipsilateral axillary lymph node. At present,it is still difficult to diagnose occult breast cancer. The diagnosis is based on the core needle biopsy and following immunohistochemical staining for the enlarged lymph nodes. If the results support,the diagnosis can be confirmed after the exclusion of other primary tumors. The standard treatment of occult breast cancer is still the mastectomy and axillary lymph node dissection. Neoadjuvant chemotherapy is an independent factor affecting the prognosis,which is also recommended before the oper-ation. Chemotherapy,radiotherapy and endocrine therapy could be chosen based on immunohistochemical results after surgical treatment. The prognosis of occult breast cancer is similar to the other types of breast cancer at the same staging.
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