耐药结核病人的耐药状况分析

摘要

Objective To investigate the current situation and the development trend in drug-resiatant tuberculosis patients.Methods On sputum cultivate of indirect method using absolute specimens of testing for drug resistance, there were analyzed the drug resistsnce in 94 eases drug-resistant TB. Results In all cases, the primary resistance is 59(62.67％ ) and the acquired resistance is 34 (36. 1％ ). The acquired resistance and MDR-TB are maximum( 19. 15％ end 10. 64％ ) in middle-aged group( tablel ). Conclusion The currant situation of TB drug resistance is quite serious. More TB control strategy must be executed strictly. The sputum cultivate of indirect method must be done with susceptibility testing for tuberculosis medicaments including the first line anti-tuberculosis drug. It is importence to the TB drug resistance testing in different age groups so that it was the basis of revision TB control plan.%目的 探讨耐药结核病人耐药状况及耐药性发展趋势.方法 根据监测点痰培养阳性的标本采用绝对浓度间接法试验进行耐药性测定,筛选出94例耐药肺结核病例,结合病例分析其耐药种类及意义.结果 初治性耐药59例,占62.67%.耐多药病例共34例,占36.1%.获得性耐药率、获得性MDR-TB以中年组最多,分别占19.15%和10.64%(见表1).结论 结核病人耐药情况比较严重,需要更严格的执行结核病控制策略.宜开展多种药物敏感试验,为修订结核病控制规划提供依据.