Objective To discuss the clinical effects of 3 pasiniazid, levofloxacin, pyrazinamide, protionamide, amikacin and cows mycobacterium bacterial vaccine/18 pasiniazid,levofloxacin and protionamide on multidrug resistant Pulmonary Tuberculosis. Methods Clinical data of 63 patients with multidrug resistant Pulmonary Tuberculosis admitted in our hospital from Feb. 2006 to Feb. 2008 were analyzed. Results Clinical symptoms improved, and the rate of pulmonary lesions absorption reached 93. 65%. After three month treatment, sputum negative conversion rate was 47. 62% ; After the full course of treatment, sputum negative conversion rate was 73. 02% ; The rate of cavity closure was 66.67%. The recurrence rate of sputum bacteria was 4. 76% after following up for 6 -24 months. Conclusions This scheme has satisfactory effect on multidrug resistant Pulmonary Tuberculosis and less side effects, which can be used for clinical treatment.%目的 探讨耐多药肺结核患者采用力克肺疾、左氧氟沙星、吡嗪酰胺、丙硫异烟胺、丁胺卡那霉素、母牛分枝杆菌菌苗治疗疗效.方法 对2006年2月～2008年2片我所收治的耐多药肺结核患者63例进行分析.结果 临床症状明显改善,肺部病灶吸收率达93.65％；治疗三个月末痰菌阴转率为47.62％,满疗程痰菌阴转率73.02％,空洞闭合率66.67％；随访6～24个月痰菌复发率为4.76％.结论 本方案治疗耐多药肺结核效果满意,药物副作用小,可用于临床治疗耐多药肺结核患者.
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