应用两种国际生存量表评价榄香稀注射液对非小细胞肺癌患者生存质量的影响

摘要

Objective To evaluate the effect of elemi dilute injection on quality of life of patients with non-small cell lung cancer by two different methods,FACT-DAS Ⅱ L4.0 and WHO.Methods 200 cases of non-small cell lung cancer patients were randomly divided into the observation group and the control group,1 00 cases in each group.All patients were given gemcitabine single-agent chemotherapy,and the observation group was additionally given elemi dilute injection.The total treatment lasted 4 cycles,28 days per cycle.Results The scores of physio-logical function,emotional function,social activities involved function and general healthy condition were obviously higher in the observation group than in the control group (P<0.05 ).There was no significance in short-term cura-tive effect between the two groups (P>0.05 ).Conclusion Elemi dilute injection can improve the body status and quality of life in the treatment of patients with non-small cell lung cancer.%目的：应用中文版FACT-L4．0和WHO DASⅡ（他评版）两种国际生存质量量表作为测定工具，评价榄香稀注射液对治疗非小细胞肺癌患者生存质量的影响，同时以传统的临床疗效评价指标作为参照。方法将200例非小细胞肺癌患者分为观察组及对照组各100例，两组均给予吉西他滨单药化疗：吉西他滨（健泽）1000 mg／m2，静脉滴注30分钟，第1、8、15天，28天为1个周期，连用4个周期。观察组使用榄香稀注射液从化疗的第1天开始用生理盐水500 ml＋榄香稀注射液50 ml静脉滴注，1天1次，连用15天，使用4个周期后评价疗效。结果经过4个周期治疗后，观察组患者在生理功能、情绪功能、角色功能、社会活动参与功能及总体健康情况等多个领域评分高于单纯化疗组，两组比较差异有统计学意义（P＜0.05），两组患者治疗近期疗效比较差异无显著性（P＞0.05）。结论榄香稀注射液可改善非小细胞肺癌患者机体状态，提高患者生存质量。