Objetive To summarize the experience in the diagnosis and treatment of meconium ileus, Help neonatal surgeon to improve the recognition of meconium ileus. Methods From 2002 to 201 2,the clini-cal data of 21 cases with meconium ileus were analyzed retrospectively. Results The 1 7 cases were simple type,4 cases were complex type,20 cases was examined with dilute gastrografin enema.5 cases of them made the definite diagnosis and 3 cases made treatment.1 4 cases of simple type underwent emergency surgery.1 0 ca-ses was performed ileum incision enema+ileostomy(7 cases was applied double barrel ileostomy,3 cases was applied Bishop-Koop ileostomy),4 cases was applied cleansing enema through the stem of appendix and 3 ca-ses of them were applied indwelling appendix stoma.4 cases of complex type were underwent emergency surger-y,2 cases of them were applied double barrel ileostomy,the orther 2 cases of them were abandoned therapy. The postoperative recovery of 1 6 cases was good,1 0 cases were performed successfully ileostomy closure in postoperative 7-1 6 weeks. Conclusion Dilute gastrografin enema is not only a kind of diagnosis method but also is a kind of therapy;Bishop-Koop ileostomy is the principal choice;For mild cases cleansing enema through the stem of appendix could be chosen.%目的：探讨新生儿胎粪性肠梗阻的诊疗经验，提高新生儿外科医师对该病的认识。方法回顾性分析本院2002年至2012年收治的21例胎粪性肠梗阻患儿临床资料。结果21例中，17例为单纯型，4例为复杂型；20例行稀释泛影葡胺灌肠造影，依靠该检查明确诊断5例，其中3例经非手术治疗痊愈。18例手术患儿中，14例单纯型行急诊手术治疗，其中10例采用肠管切开灌洗＋肠造瘘术（7例采用回肠双腔造瘘术，3例采用回肠Bishop-Koop造瘘术），4例采用阑尾切除、肠内灌洗术（3例留置阑尾造瘘管）。4例复杂型均行急诊手术，2例采用回肠双腔造瘘术，2例术中放弃治疗。18例手术患儿中，16例术后恢复良好，10例造瘘患儿术后7～16周行造瘘还纳术。结论稀释泛影葡胺灌肠造影既能有效协助诊断，又能使少部分患儿治愈；Bishop-Koop造瘘术为首选术式；胎粪较易排出的患儿可选用阑尾切除、肠内灌洗术。
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