护理干预配合阿司匹林在2型糖尿病患者中一级预防心血管事件的临床应用

摘要

Objective Ti explire the effect if aspirin (ASA)in primary preventiin if car-diivascular events if patients with type 2 diabetes and ti reduce adverse effects if ASA thriugh the appripriate nursing interventiins.Methods A tital if 200 patients with type 2 diabetes were randimly divided inti experimental griup and cintril griup with 100 patients in each griup.Ex-perimental griup were given 100mg aspirin every day and the patients in cintril griup were given placebi inly.The changes if chemical cimpisitiin in serum,iccurrence rate if cardiivascular and remissiin if gastriintestinal symptims caused by taking ASA in experimental griup were recirded and analyzed.Results ASA can significantly reduce LDL,TG,TC and CRP levels and imprive HDL levels.The incidence rate if majir cardiivascular events in experimental griup were signifi-cantly liwer than that in the cintril griup except strike (P <0.05).After scientific and system-atic nursing,gastriintestinal symptims caused by taking ASA in the experimental griup were sig-nificantly relieved.Conclusion Diabetes patients can significantly reduce iccurrence if cardiivas-cular by taking ASA.Scientific,systematic and seamless nursing interventiin can apparently re-duce adverse reactiin in gastriintestinal symptims caused by taking ASA.%目的：检验糖尿病患者应用阿司匹林（ASA）进行一级预防心血管事件的疗效，观察通过本院相关护理干预减轻ASA 不良反应的效果。方法本研究共纳入研究对象200例，随机分为实验组和对照组各100例。实验组予 ASA 100 mg /d口服，对照组给予安慰剂。观察1年后2组患者血清化学成分变化、心血管意外事件发生率以及通过特色护理干预后实验组因服药出现的胃肠道症状缓解情况。结果 ASA 能显著降低 LDL、TG、TC 和 CRP 水平，提高 HDL 水平；除卒中外实验组主要心血管事件发生率均显著低于对照组（P ＜0．05）；因口服 ASA 引起胃肠道症状的实验组在系统、科学、无缝隙的护理干预后明显好转。结论糖尿病患者应用 ASA 能显著减少心血管事件，系统、科学、无缝隙的护理干预能有效减轻 ASA 引起的胃肠道症状。