Objective To investigate multiple viral antigens in pediatric patients with respiratory infection in Yangzhou.Methods A total of 17 691 children with respiratory infection admitted in our hospital between January 2011 and December 2011 were tested with direct immunof-luorescence method.A total of 7 kinds of virus antigens were detected,including adenovirus (ADV),respiratory syncytial virus (RSV),parainfluenza virus Ⅰ,Ⅱ,Ⅲ(PIV Ⅰ,Ⅱ,Ⅲ),influenza virus A/B(IFA/B).Its epidemiological characteristics was analyzed.Results There were altogether 1 991 positive cases,the detection rate was 11.25％ (1 991/17 691),in which the proportion of RSV was 60.12％ (1 197/1991),followed by PIV llⅢ 14.27％ (284/1 991),ADV 8.04％ (160/1 991),PIV Ⅰ 5.42％ (108/1 991),IFA5.27％ (105/1 991),IFB 4.07％ (81/1 991),PIVⅡ 2.81％ (56/1 991).There was significant difference between male and female in the detection rate of respiratory virus.Respiratory virus detected rate in 1 month to ＜ 1 year old was 59.81％ (1 191/1 991),single virus detection rate was the highest.The detection rate of virus for positive was the highest in winter,accounting for 51.88％ (1 033/1 991),and the lowest in summer for 10.35％ (206/1 991).Conclusion Respiratory virus infection in Yangzhou is influenced by age,season and gender,with infants and young children aged 1 month to 1 year in high-risk infection,and RSV infection occurs mostly,and the male are most likely to be infected in winter.%目的 分析扬州地区儿童呼吸道感染病毒病原体的感染情况.方法 应用直接免疫荧光法检测2011年1月-2016年12月扬州地区17 691例呼吸道感染儿童鼻咽分泌物呼吸道腺病毒(ADV)、合胞病毒(RSv)、副流感病毒Ⅰ、Ⅱ、Ⅲ(PIV Ⅰ、Ⅱ、Ⅲ)、流感病毒A/B(IFA/B)病毒抗原并分析其流行病学特征.结果 在17 691例标本中,共检出病毒阳性标1 991例,检出率11.25％(1 991/17 691);在1 991例阳性标本中,RSV占60.12％(1 197/1 991),其他依次为PIV Ⅲ14.27％(284/1 991)、ADV 8.04％(160/1 991)、PIV Ⅰ 5.42％(108/1 991)、IFA 5.27％(105/1 991)、IFB 4.07％(81/1 991)PIVⅡ2.81％(56/1 991).RSV检出率存在性别差异.1月～＜1岁组呼吸道病毒检出病例占总检出率的59.81％(1 191/1 991);单项病毒检出率在4组人群中均居首位.冬季是检出病毒阳性占比最高的季节,为51.88％(1 033/1 991);夏季检出率最低,为10.35％(206/1 991).结论 扬州地区呼吸道病毒感染受年龄、季节和性别的影响,RSV感染最多见,以1月＜1岁婴幼儿为主,冬季好发,并且男性较女性更易感.
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