脉血康胶囊联合经皮冠状动脉介入术对急性冠脉综合征患者血小板聚集率及超敏C-反应蛋白的影响

摘要

Objective To explore the effect of maixuekang capsule combined with percutaneous coronary intervention (PCI) on platelet aggregation rate and high sensitivity C-reactive protein (hs-CRP) in patients with acute coronary syndrome.Methods Totally 124 patients with acute coronary syndrome by PCI were divided into RTT group (conventional treatment) and MKT group (maixuekang capsule treatment),62 cases in each group.Platelet aggregation rate and serum hs-CRP concentration were compared at the time points of before operation,12 h after operation and 30 d after operation.Results In patients with acute coronary syndrome,platelet aggregation rate significantly increased at 12 h after operation,and serum hs-CRP concentration increased significantly (P ＜0.05).After 30 days of treatment,there were significant differences in platelet aggregation rate and hs-CRP between two groups (P ＜ 0.05).The incidence rate of cardio cerebral events in MKT group was lower than that in RTF group.Conclusion Maixuekang capsule can reduce the platelet aggregation rate and hs-CRP concentration in patients with acute coronary syndrome after PCI.%目的 探讨脉血康胶囊联合经皮冠状动脉介入术(PCI)对急性冠脉综合征患者血小板聚集率、超敏C-反应蛋白(hs-CRP)的影响.方法 124例行PCI的急性冠脉综合征患者分为RTT组(常规治疗)和MKT组(脉血康胶囊治疗)各62例.比较术前、术后12 h及术后30 d血小板聚集率、血清hs-CRP浓度.结果 急性冠脉综合征患者术后12 h血小板聚集率显著升高,血清hs-CRP浓度显著上升(P＜0.05);经脉血康胶囊治疗30 d后,2组血小板聚集率、hs-CRP比较有显著差异(P＜0.05).MKT组心脑血管事件发生率低于RTT组.结论 脉血康胶囊可以降低PCI术后血小板聚集率与hs-CRP浓度.