Objective To investigate the use of dynamic blood glucose testing to assess the efficacy of insulin detemir and its effects on the cardiovascular and weight negative. Methods Our hospital nearly 4 years with type 2 diabetes patients with a total 60 cases,the use of systematic reviews glucose monitor blood glucose control efficacy,safety and impact on body weight and the correlation with cardiovascular events. Results 60 patients with type 2 diabetes take a different treatment. The glycated hemoglobin(HbA1C),fasting blood glucose(FBG),2 h postprandial blood glucose(PBG)of A and B group were significantly lower than group C. The difference was statistically significant( P 0. 05). Body mass index among the three groups(BMI)and insulin dosage difference was not statistically significant. The time blood glucose of A and B group were significantly lower than group C. The incidence of hypoglycemia of group A and B also lower than group C,the difference was statistically significant( P 0.05）。三组间体质指数（ BMI）和胰岛素用量比较差异无统计学意义，两两组间比较A组BMI 稍低于B组和C组，A组和B组胰岛素用量稍低于C组，但差异均无统计学意义（ P >0.05）；三组间A组、B组血糖达标时间均明显低于C组，低血糖发生率也低于C组，差异具有统计学意义（ P <0.05），但A组与B组比较差异无显著性；血糖波动和血脂波动方面，A组、B组较C组好，差异具有统计学意义（ P <0.05）。随访期间发现：A组心血管事件发生率为30.0%（6/20），B组心血管事件发生率为40.0%（8/20），C组心血管事件发生率为65.0%（13/20）。A组和B组较C组心血管事件发生率低，差异有显著性（ P <0.05）。结论利用动态血糖监测发现地特胰岛素疗效较中效胰岛素治疗效果较好，在控制血糖、血脂方面较中效胰岛素有较大的优势，还能降低心血管发生率；而甘精胰岛素与地特胰岛素效果相当。
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