睡眠中发作症状的脑电图特征及其与睡眠分期的关系

摘要

目的：探讨睡眠中发作症状的脑电图特征及其与睡眠分期的关系。方法统计分析2012年9月至2014年9月收治的86例睡眠中发作症状患者的临床资料。结果夜发性额叶癫痫患者的痫样波检出率57.1%（12/21）显著高于睡眠肌阵挛、夜惊症、梦游症、梦魇患者9.7%（3/31）、18.8%（3/16）、0、0（ P ﹤0.05）；86例患者中，NREMⅠ期、NREMⅡ期是睡眠肌阵挛集中发生的时期，NREMⅢ期、NREMⅣ期是夜惊症、梦游症集中发生的时期，REM期是梦魇集中发生的时期，NREMⅠ期、NREMⅡ期是夜发性额叶癫痫主要发生的时期，其次为NREMⅢ期、NREMⅣ期，最后为REM期。结论不同睡眠中发作症状的脑电图特征差异显著，和睡眠分期关系密切，临床可以依据脑电图特征对睡眠中发作症状患者的疾病类型进行诊断，从而为及时准确地治疗和改善患者预后提供良好的前提条件。%Objective To explore the characteristics of electroencephalographic features in onset of symptoms during sleep and sleep stag-ing. Methods The clinical data of 86 patients with onset of symptoms during sleep admitted and treated in the department of internal medicine in this hospital during September 2012 to September 2014 were reviewed and analyzed. Results The detection rate of epileptiform wave in patients with nocturnal frontal lobe epilepsy was 57. 1%(12/21),it was significantly higher than that of patients with sleep myoclonus 9. 7%(3/31), night terrors,18. 8%(3/16),sleepwalking(0)and nightmare(0)( P ﹤0. 05). Among these 86 patients,NREM I and NREM II were set in the period of sleep myoclonus,NREM III and NREM IV were night terror,set in sleepwalking concentrated period,the REM period was nightmare concentrated period,NREM I and NREM II were periods for occurring sleep myoclonus,NREM III and NREM IV were the periods for occurring night terror and sleepwalking,REM was the period for occurring nightmare,NERM I and NERM II were the main periods for occurring nocturnal frontal lobe epilepsy,the next periods were NREM III and NREM IV,and REM was the final period. Conclusion Different onset of symptoms during sleep has significant difference in EEG characteristics,they had close relationship with sleep staging. According to the features of EEG,the types of disease during sleep can be timely and accurately diagnosed,thus accurate treatment can be carried out for these patients and provide good condition for these patients and improve their prognosis.