超声内镜、染色法及窄带成像技术联合使用对早期食管癌的诊断价值

摘要

Objective To study the clinic value of narrow - band imaging combined with staining and endoscopic ultrasonography in the diagnosis of early esophageal cancer. Methods Four hundred twenty - four patients with suspected esophageal mucosal lesions under conventional white light endoscopy were randomly assigned to the observation group and control group,212 cases in each group,the control group was examined with conventional white light endoscopy;in addition to the conventional white light endoscopy examination,the observation group was examined with narrow - band imaging combined with staining and endoscopic ultrasonography. The sensitivity,specificity and accuracy of the examinations between two groups were compared. Results Cancer was found in 69 cases(32. 55% )in observation group and in 72 cases(33. 96% )in con-trol group( P > 0. 05). The sensitivity,specificity and accuracy of detection were 93. 02% ,82. 84% ,and 84. 91% respectively,in observation group,while they were 82. 86% ,75. 71% ,and 76. 89% respectively in control group. The detection accuracy in observation group was signifi-cantly higher than the control group( P 0. 05). Con-clusion The combined use of narrow - band imaging,staining and endoscopic ultrasonography can significantly improve the accuracy of diagnosis of early esophageal cancer.%目的：研究超声内镜、染色法及窄带成像技术联合使用在诊断早期食管癌中的临床价值。方法选取2012年12月至2014年11月行普通白光胃镜检查怀疑食管黏膜病变的患者为研究对象，共424例，将患者按随机数字法分为观察组和对照组，各212例，对照组采用普通白光内镜进行检查，观察组在对照组检查基础上加用超声内镜、染色法及窄带成像技术检查，比较两组检查方法的灵敏度、特异度及准确率。结果观察组检出癌69例，癌检出率为32.55%；对照组检出癌72例，癌检出率为33.96%。两组癌检出率差异无统计学意义（ P >0.05）。观察组检测灵敏度、特异度、准确率分别为93.02%、82.84%、84.91%，对照组分别为82.86%、75.71%、76.89%。观察组检测方法准确率明显高于对照组，差异有统计学意义（ P 0.05）。结论普通白光内镜检查用于筛查早期食管癌具有较高的检出率、灵敏度及特异度，但对可疑病变患者可进一步行超声内镜、染色法联合窄带成像技术检查，以提高食管癌诊断的准确率。