Objective To study hemodynamic effects of noradrenaline during valve replacement in severely ill patients. Methods Twenty-seven valvular heart disease patients undergoing valve replacements were divided into two groups based on their vasoactive drugs: group NA[noradrenaline (NA) and dobutamine (Dob),.1=12] and group AD [adrenaline (AD) and dobutamine (Dob),?= 15]. Pulse induced continuous cardiac output (PiCCO)and arterial/vein blood gas analysis were monitored at the follow point; before operation (To) , the end of CPB (T, > , 6 h after operation(Tz ) , 24 h after operation 展开▼
