李贵教授中西医结合治疗小儿迁延性难治性支原体肺炎的经验总结

摘要

Objective To compare the curalive effecl of inlegraling Lradilional and weslern medicine melhods of Professor Li Gui and that of the weslern medicine on children with persislenl refraclory mycoplasma pneumoniae pneumonia. Methods The conlrol group was Irealed with azilhromycin injeclion I. V. Once per day for seven days. The palienls withoul satisfying effecl were given three more days of the Irealmenl after a four-day-inlerval. After that, the palienls in the conlrol group was given melhylprednisolone I. V. For three lo five days. Meanwhile, they were given Yi Tan Jing, a compound solution of clenbuterol hydrochloride and ambroxol hydrochloride, from the day they came lo hospilal. The Irealmenl group was Irealed with azilhromycin injeclion I. V. Once per day for seven days. Those withoul satisfying effecl were Irealed with differenl lypes of Chinese lradilional medicine inslead of weslern medicine. Results Time for the Irealmenl group lo relief fever and cough was significantly shorler lhan that of the conlrol group ( P < 0. 01) . And lime for the Irealmenl group lo disappearance of the moisl rale and wheezing rale was also significantly shorler lhan that of the conlrol group ( P < 0. 05 and 0. 01). After being given the Chinese lradilional medicine, the Irealmenl group slayed in hospilal for significantly fewer days lhan the conlrol group (P <0. 05). The total lime for the Irealmenl group lo slay in hospilal was also shorler lhan that of the conlrol group, but the difference was nol statistically significant. Conclusion The effecl of the combination of Chinese tradilional medicine with the effect of clearing heal and deloxicalion, quickening the blood and transform stasis, forlifying the spleen and boosling qi and weslern medicine on the children with persislenl refraclory mycoplasma pneumoniae pneumonia was much betler lhan that of the conlrol group.%目的 比较李贵教授中西医结合方法和西医方法治疗小儿迁延性难治性支原体肺炎的效果.方法 对照组以阿奇霉素注射液静脉滴注,每日1次,疗程7 d,如效果不满意间隔4 d再用3 d,之后再加用甲泼尼龙静脉滴注,3～5 d同时口服易坦静.治疗组以阿奇霉素静脉点滴7 d,效果不满意者停西药,按辩证分型加用不同方剂中药治疗.结果 治疗组发热减轻和消退时间、咳嗽减轻和消退时间明显短于对照组,差异有统计学意义(P<0.01);治疗组湿啰音、哮鸣音减少和消失时间明显短于对照组,差异有统计学意义(P<0.05).治疗组用药后住院天数明显少于对照组,差异有统计学意义(P<0.05).结论 中药与西药联合治疗小儿迁延性难治性支原体肺炎效果明显优于组间均治疗组调痰、瘀、闭、虚是该类肺炎的病因病机.