首页> 中文期刊> 《滨州医学院学报》 >双水平通气模式进行改良叹气法肺复张在外源性急性呼吸窘迫综合征病人中的应用研究

双水平通气模式进行改良叹气法肺复张在外源性急性呼吸窘迫综合征病人中的应用研究

         

摘要

Objective To study the clinical effects of BILEVEL modified type and pressure control ventilation (PCV ) in the therapy of exogenous ARDS .Methods 50 cases of patients with exogenous ARDS were undergoed two RM at different times , respectively according to crossover design method BILEVEL modified type ,pressure control ventilation (PCV) .Mean arterial blood pressure(MAP) ,central venous pressure(CVP) ,oxygenation index ,lung compliance were recorded before and after RM and analysised .Results Oxygenation index and lung compliance were improved obviously in a short time after RM ,30min and 1 hour ungraded extent of PCV group were less than BILEVEL modified type groups obviously ,after two hours ,dates of the two groups were similar .After RM ,heart rate and CVP were increased ,MAP was decreased in a short time ,changes of PCV group were larger than BILEVEL modified type group ,after 30 min ,dates of two groups were similar .Conclusions For the patients with exogenous ARDS undergone RM ,BILEVEL modified type method was effective on improving oxygenation index and lung compliance ,and had fewer effects on hemodynamics .%目的:探讨使用双水平通气模式(BILEVEL)进行改良叹气法肺复张(RM)与压力控制法(PCV)肺复张应用于外源性急性呼吸窘迫综合征(ARDS)病人的效果。方法将外源性急性呼吸窘迫综合征病人50例,按照交叉设计的方法在不同时段分别应用BILEVEL ,PCV两种肺复张,记录肺复张前后病人平均动脉压,中心静脉压,氧合指数,肺静态顺应性等指标,进行对照研究。结果两组患者RM后短时间内氧合指数和肺静态顺应性指标显著改善,PCV组30 min、1 h的增加幅度较BILEVEL组明显减少,2 h时两组数据之间无明显差别。RM 后病人短时间内均有心率增快,CVP上升,MAP下降,PCV组变化幅度更大,30 min后两组数据之间无明显差别。结论对于肺外源性 ARDS行RM ,BILEVEL肺复张对肺顺应性和氧合改善效果好,对血流动力学影响较小。

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