目的：探讨输尿管内留置巴德双J管治疗晚期恶性肿瘤继发输尿管梗阻的临床效果。方法回顾性分析我院收治的54例晚期恶性肿瘤继发输尿管梗阻患者，分别通过输尿管内置入巴德双J管和普通双J管用于解除梗阻。其中置入巴德双J管患者20例（观察组），普通双J管患者34例（对照组）。比较两组患者血肌酐与血尿素氮下降幅度、并发症发生情况及输尿管梗阻复发率。结果经治疗1周后，两组患者血肌酐与血尿素氮均较治疗前下降明显（P＜0．05），且观察组下降幅度大于对照组（P＜0．05）。其少尿、无尿症状较前均有所缓解，尿液引流通畅。随访半年，观察组尿路感染、出血发生率均低于对照组（P＜0．05）；两组慢性疼痛发生率及输尿管梗阻复发率比较，差异均无统计学意义（P＞0．05）。结论输尿管内留置巴德双J管是治疗晚期恶性肿瘤继发输尿管梗阻较为理想的方法，值得临床推广应用。%Objective To investigate the clinical effect of double J ureteral catheter in the treatment of patients with ureteral obstruction after advanced malignant tumor.Methods A retrospective analysis of Fifty-four cases of advanced malignant tumor with u-reteral obstruction,respectively,through were placed the ureter double J tube and ureteral stent into the common double J tube to relieve the obstruction.The ureteral stent into the Bard double J tube 20 patients (observation group)and ureteral stent into the common doub-le J tube of 34 patients with (control group).Compared blood creatinine and blood urea nitrogen of the two groups and the incidence of complications and the recurrence rate of ureteral obstruction.Results After 1 week's treatment,serum creatinine and blood urea nitro-gen of the two groups were significantly lower than those before treatment(P <0.05),and those of the observation group were signifi-cantly lower than the control group(P <0.05).Symptoms of oliguria and anuria have been eased,urine drainage unobstructed.During follow-up for six months,the incidence of urinary tract infection and bleeding in the observation group was lower than that in the control group(P <0.05).There was no significant difference between the two groups in the incidence of chronic pain and the recurrence rate of ureteral obstruction(P >0.05).Conclusion Indwelling double J tube in ureter is an ideal method for the treatment of ureteral ob-struction secondary to advanced malignant tumors,which is worthy of clinical application.
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