多肿瘤标志物蛋白芯片检测系统的临床应用

摘要

Objective:To investigate the clinical value of multi-tumor markers protein biochip detective system ( C-12 system). Methods:The serum of 280 malignant tumor patients and 106 healthy people were detected by C-12 system. The sensitivity and specificity of the system in all cases were analyzed. Results:Two hundred and fourty-two postive cases in 280 malignant tumor patients and 7 postive cases in 106 healthy people were detected by C-12 system. The sensitivity of C-12 system in 280 malignant tumor patients and 106 healthy people were 86. 43% and 93. 40%, respectively. Conclusions:C-12 system is available for the clinical laboratory diagnosis of tumor,especially for health examination and tumor screening. Detecting multiple indicators at the same time can enhance the detection rate and accuracy,which has certain supplementary meaning in judging the tumor source.%目的：探讨多肿瘤标志物蛋白芯片(C-12)检测系统的临床应用价值。方法：应用C-12检测系统，对280例临床常见的恶性肿瘤患者以及106名健康对照者血清进行检测，分析其灵敏度、特异性，比较2组差异。结果：C-12检测系统对肿瘤患者检测阳性242例，敏感性86.43%；健康对照组106名中阳性7例，特异性93.40%。结论：C-12检测系统可用于临床肿瘤实验室诊断，更适宜于健康体检及肿瘤普查。多个指标间同时检测，可提高检测率及准确度，并对肿瘤来源判断有一定的辅助意义。