觉醒型缺血性卒中与6h内缺血性卒中CT灌注成像特点比较

摘要

目的:比较觉醒型缺血性卒中(wake-up ischemic strokes,WUIS)与6 h内缺血性卒中(ischemic strokes,IS)的临床特征及CT灌注成像(CTP)特点.方法:WUIS患者38例(WUIS组),明确IS发病时间6 h内患者42例(对照组),均行多模式CT检查[CT-CTP-CT血管成像(CTA)].结果:2组患者梗死区和半暗带区数量、体积与CTP模式差异均无统计学意义(P>0.05);2组患者CTP、CT和MRI Alberta卒中项目早期CT评分(ASPECTS评分)差异均无统计学意义(P>0.05),初始CT ASPECTS评分均明显高于CTP及3 d后CT或MRI ASPECTS评分(P<0.01);WUIS组NIHSS评分显著高于对照组(P<0.01).结论:WUIS患者的CTP特点与发病6 h内IS患者类似.%Objective:To compare the clinical and CT perfusion imaging(CTP) characteristics between the wake-up ischemic stroke ( WUIS) and ischemic stroke( IS) within 6 hours. Methods:Thirty-eight patients with WUIS and 42 patients with IS within 6 hours were divided into the WUIS group and control group. All patients were examined using the multi-mode CT. Results:The differences of the number and size of infarct,and penumbra,and the CTP pattern between two groups were not statistically significant(P>0. 05),and the differences of the ASPECTS scores of CT,MRI and CTP between two groups were not statistically significant(P >0. 05). The ASPECTS score of initial CT was significantly higher than that of CTP and CT or MRI after 3 days(P<0. 01). The NIHSS score in WUIS group was significantly higher than that in control group(P<0. 01). Conclusions:The characteristics of CTP in WUIS patients are similar to the patients with IS within 6 hours.