目的 评价温阳健脾法治疗急性中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)的临床疗效.方法 将临床确诊为急性CSC的74例患者(75只眼)纳入研究,随机将其分为观察组(40例40眼)和对照组(34例35眼),观察组予自拟温阳健脾之中药汤剂,对照组予口服改善微循环药物(复合维生素B、维生素C、肌苷)治疗,两组均治疗6周,治疗前后分别观察患者黄斑中心凹视网膜厚度(central macular thickness,CMT)及最小分辨视角对数值(logarithm of minimum angle of resolution,logMAR).结果 治疗后两组视力较治疗前均有所提高(P＜0.05),且治疗组优于对照组(P＜0.05);治疗后两组CMT均低于治疗前(P＜0.05),且治疗组下降值显著大于对照组(P＜0.05).结论 温阳健脾法是治疗急性CSC的一种有效方法.%Objective To investigate the clinical effect of yang-warming and spleen-strengthening method in the treatment of acute central serous chorioretinopathy (CSC).Methods A total of 74 patients (75 eyes) with a confirmed diagnosis of acute CSC were enrolled and randomly divided into observation group (40 patients with 40 eyes) and control group (34 patients with 35 eyes).The patients in the observation group were given self-made yang-warming and spleen-strengthening traditional Chinese medicine (TCM) decoction,and those in the control group were given oral drugs to improve microcirculation (vitamin B complex,vitamin C,and inosine).The course of treatment was 6 weeks for both groups.Central macular thickness (CMT) and logarithm of minimum angle of resolution (logMAR) were observed for both groups before and after treatment.Results Both groups showed a significant increase in eyesight after treatment (P＜0.05),and the observation group had a significantly greater increase than the control group (P＜0.05).Both groups showed a significant reduction in CMT after treatment (P＜0.05),and the observation group had a significantly greater reduction than the control group (P＜0.05).Conclusion Yang-warming and spleen-strengthening method is effective in the treatment of acute CSC.
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