The researches on the oocyte's cryotolerance improvement of four cryoprotectant9, such as cytochalasin B, taxol, caffeine and gluta-thione were summarized. And the relationship between the expression level ol two apoptosis gene Bcl-2 and Bax and the oocyte apoptosis was analyzed.%系统综述了细胞松弛素B、紫杉醇、咖啡因和谷胱甘肽4种冷冻保护剂在增强卵母细胞抗冻能力方面的研究,并分析了Bcl-2和Bax 2种凋亡基因的表达程度与卵母细胞凋亡之间的关系.
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