拟诺卡氏菌次级代谢产物的研究

摘要

[ Objective ] The aim was to study the chemical composition of the secondary metabolites of Nocardiopsis sp. [ Method ] Some chromatographic methods were used to separate and purify the chemical constituents whose structures were identified by NMR and MS. [ Result]Four monomeric compounds were separated and identified as dictamnine ( 1 ), 6-hydroxy-4-( 4- hydroxyphenyl)-7-methoxycoumarin (2), 4-isopropyl-benzoic acid (3) and indole-2-carboxylic acid (4). [Conclusion] All of them were first isolated from the Nocardiopsis sp.%[目的]研究拟诺卡氏菌次级代谢产物的化学成分.[方法]应用多种色谱方法进行分离和纯化,并用NMR和MS等方法解析其结构.[结果]得到4个单体化合物,其结构分别鉴定为白鲜碱、6-羟基-4-(4-羟苯基)-7-甲氧基香豆素、4.异丙基苯甲酸、β-吲哚甲酸.[结论]所有化合物均为首次从该菌中分离得到.