血栓抽吸对急性ST 段抬高型心肌梗死患者的疗效观察

摘要

目的：评价血栓抽吸治疗急性ST 段抬高心肌梗死患者的临床疗效。方法：选择行急诊冠状动脉介入治疗（ PCI）的急性ST段抬高心肌梗死患者97例，冠状动脉造影证实有明显血栓负荷，其中观察组49例介入治疗前给予抽吸导管抽吸血栓，对照组48例行传统PCI术，观察两组临床疗效及安全性。结果：治疗组梗死血管的TIMI3级血流、术后1 h ST段回落百分比均优于对照组（ P﹤0.05），治疗组球囊使用少于对照组，两组在植入支架、住院期间主要心血管不良事件、术后三个月随访测定左室射血分数、左室舒张末期内径等方面比较差异无统计学意义（ P﹥0.05）。结论：血栓抽吸导管治疗急性ST段心肌梗死可减少无复流或慢血流发生，减少手术中球囊使用，同时不增加手术的风险，有利于改善心肌灌注，改善预后。%Objective To study the effect of thrombus aspiration during primary PCI in patients with acute ST segment elevation myo-cardial infarction. Method To choose underwent emergency coronary intervention( PCI)of 97 cases of patients with acute ST segment ele-vation myocardial infarction,The patients with AMI undergoing primary PCI and receiving aspiration thrombectomy catheter( n=48 )were enrolled in study group,and those who had similar coronary angiography results and basic characteristics but only received routine PCI( n=46 )were enrolled in control group. To observe the clinical efficacy and safety. Results Treatment group in the infarction vascular blood flow TIMI3 level and 1 h after ST segment fell percentage were better than control group( P﹤0. 05),the treatment group used in balloon was less than the control group,two groups during MACE had no significant difference After 3 months,LVEF and LVEDd also had no significant difference. Conclusion Thrombus aspiration catheter in treatment of AMI can reduce no reflow or slow blood flow,reduce the balloon is used in the operation,do not increase the risk of surgery at the same time,to improve myocardialperfusion,and improve the prognosis.