Objective To explore the influence of lifestyle intervention on blood glucose in patients with early stage of diabetes based on TCM constitution identification. Methods 102 patients with early stage of diabetes were randomly divided into treatment group (55 cases) and control group (47 cases). The control group was given a simple lifestyle intervention program and the observation group was given lifestyle intervention program of TCM constitution identification. The two groups were observed for 6 months. Fasting and postprandial 2 h blood glucose, glycosylated hemoglobin, and insulin resistance index were the main observation items. Results The fasting and postprandial 2 h blood glucose(mmol/L), glycosylated hemoglobin (%) and insulin resistance index in the control group were 5.92 ± 0.28, 7.93±1.17, 5.62±0.20, 3.16±0.74; 86±0.75. There was significant difference between the two groups(P<0.05) Conclusion Compared with the simple lifestyle intervention, the lifestyle intervention based on TCM constitution identification can further change blood glucose spectrum and insulin resistance, so it is worth further research and demonstration.%目的 探讨基于中医体质辨识的生活方式干预对糖尿病前期患者血糖变化的影响.方法 将符合标准的糖尿病前期患者102例随机分为治疗组(55例)和对照组(47例).对照组给予单纯生活方式干预方案,观察组给于中医体质辨识后的生活方式干预方案.2组均观察6个月,主要观察空腹及餐后2 h血糖、糖化血红蛋白、胰岛素抵抗指数的差异.结果 对照组患者干预后空腹及餐后2 h血糖(mmol/L)、糖化血红蛋白(%)、胰岛素抵抗指数分别为5.92±0.28,7.93±1.17,5.62±0.20,3.16±0.74;观察组干预后以上4项指标分别为5.53±0.36,7.23±0.87,5.34±0.24,2.86±0.75,2组间各项数据差异均有统计学意义(P<0.05).结论 与单纯生活方式干预相比较,基于中医体质辨识后的生活方式干预能进一步改善患者血糖谱和改善胰岛素抵抗.
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