瑞芬太尼丙泊酚全凭静脉麻醉与静吸复合麻醉用于腹腔镜胆囊切除术临床效果对比分析

摘要

Objective To analyze and compare the effect of remifentanil-propofol intravenous anesthesia (RPIA) and intravenous-inhalation combined anesthesia (IICA) on laparoscopic cholecystectomy (LC).Methods 100 patients during 2010-2012 were randomly divided into 2 groups,the experimental group accepted RPIA while the control group accepted IICA.Results The experimental group had less fluctuation in SBP,DBP and HR than control group at the point of pneumoperitoneum start and finish,operation finish and extubation (P＜0.05).The experimental group had shorter time of auto breathing and extubation and higher score of OAAS than control group (P＜0.05).The experimental group had less adverse reaction of 4％(2/50) than control group as 10％(5/50)(P＜0.05).Conclusion The remifentanil-propofol intravenous anesthesia is safe and stable on LC and causes less fluctuation and adverse reaction.%目的 对比分析瑞芬太尼丙泊酚全凭静脉麻醉与静吸复合麻醉在腹腔镜胆囊切除术(LC)中的临床效果.方法 2010年至2012年于我院接受LC的100例患者随机分为实验组和对照组各50例,实验组瑞芬太尼丙泊酚全凭静脉麻醉,对照组静吸复合麻醉,对两组患者术中血流动力学变化及术后苏醒情况进行观察比较.结果 气腹建立与结束后、手术结束后及拔管后实验组收缩压、舒张压、心率波动幅度均显著小于对照组(P＜0.05).实验组自主呼吸恢复时间、拔管时间均短于对照组,拔管后OAAS评分显著高于对照组,差异有显著性(P＜0.05).实验组发生恶心、呕吐等不良反应2例,对照组5例.结论 瑞芬太尼丙泊酚全凭静脉麻醉用于LC安全可靠,血压波动小,术后不适感少,是一种较好的麻醉方法.