明胶空心胶囊中残留氯乙醇和环氧乙烷的测定方法改进

摘要

Objective To improve the method for detecting residual chlorine ethylene oxide and ethanol in gelatin hollow capsules.Methods The 10％ polyethylene glycol packed column was replaced by a large caliber capillary column.Detection was conducted with FID and TCD as detectors.Results The large caliber capillary column was superior to the packed column with stationary liquid of 10％ polyethylene glycol in the separation effect.FID was better than ECD for detection.Conclusions This new method has better repeatability and separation effect.%目的 改进明胶空心胶囊中残留氯乙醇和环氧乙烷的测定方法.方法 采用大口径毛细管柱代替标准方法中规定的10％聚乙二醇填充柱,检测器采用FID和TCD,分别进行测定.结果 对氯乙醇和环氧乙烷的测定中,采用大口径毛细管柱分离效果优于固定液为10％聚乙二醇填充柱；检测器采用FID优于ECD.结论 该方法重现性佳,分离效果好.