孕中期超声检测子宫动脉血流用于预测早发型子痫前期的价值

摘要

目的 探讨孕中期超声监测子宫动脉血流动力学变化在早发型子痫前期临床诊治中的应用价值.方法 应用彩色多普勒测量妊娠妇女在孕20～23+6周及孕24～28周的子宫动脉血流PI(搏动指数)、RI(阻力指数)、S/D(收缩期峰值流速/舒张末期流速),追踪随访孕妇中晚期妊娠过程及分娩情况,比较早发型子痫前期组和正常妊娠对照组子宫动脉血流参数的差异.结果 根据妊娠结局,获取早发型子痫前期组21例,正常对照组40例,早发型子痫前期组妊娠20 ～ 23+6周及妊娠24～28周子宫动脉PI、RI、S/D均高于正常对照组,两者比较差异有统计学意义(P＜0.05).结论 早发型子痫前期子宫动脉血流动力学较正常妊娠妇女有较大不同,孕中期子宫动脉血流参数可作为一项辅助指标协助临床医生筛查出早发型子痫前期的高危人群.%Objective To investigate the practical value of monitoring uterine hemodynamics with ultrasound during second trimester in clinical diagnosis and treatment on early-onset preeclampsia.Methods Doppler ultrasound was given to observe PI,RI and S/D of uterine arteries in 20-23+6 weeks and 24-28 weeks for all pregnant women,follow up observation was conducted to pregnant women during pregnancy and childbirth,then we compared the group uterine artery blood flow parameters of early-onset preeclampsia with normal pregnancy.Results According to pregnancy outcomes,access to 21 cases of early-onset preeclampsia and 40 cases of normal control group,patients with early-onset preeclampsia had higher uterine arterie PI,RI and S/D than the those of normal control group in 20-23+6 weeks and 24-28 weeks,the difference has statistical significance,P ＜ 0.05.Conclusion The early-onset preeclampsia compared with normal,uterine artery blood flow velocity of pregnant women is quite different,uterine artery blood flow parameters can be used as a secondary indicator to assist clinicians of screening risk populations with early-onset preeclampsia during second trimester.