Periodontitis of alveolar bone loss is a common inflammatory destructive periodontal disease that leads to loss of the supporting structures of the teeth. T lymphocytes play an important role in the occurrence and development of periodontal disease. On one hand, T cells activated by antigens of periodontal pathogens are necessary for immune defense against periodontal pathogens. On the other hand, activated T cell is not only important regulator of activation or maturation of osteoclasts and bone resorption, but also the important damage cells in periodontal alveovar bone loss. This review elutidated the research progress on periodontitis of alveolar bone loss, T cells in the alveolar bone loss in periodontal diseases, T cells and interferon-γ on the role of osteoclasts.%牙周炎性牙槽骨吸收是常见的牙周组织炎症性破坏性疾病,是导致牙丧失的主要原因.T细胞在牙周炎的发生发展过程中发挥了重要的作用.一方面,牙周致病菌抗原活化T细胞是机体抗牙周致病菌感染所必需；另一方面,活化的T细胞是破骨细胞分化成熟和骨吸收活性的重要调节细胞,也是牙周炎性牙槽骨吸收的损伤细胞.本文就牙周炎性牙槽骨吸收,T细胞在牙周炎性牙槽骨吸收中的作用,T细胞和干扰素-γ对破骨细胞的作用等研究进展作一综述.
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