卵清蛋白制作哮喘模型的研究进展

摘要

Animal models are of great value in the study of allergic bronchial asthma.There are a varie-ty of methods to build asthma models,and model evaluation lacks standardized criteria.By retrieval analyzing the recent articles about asthma animal experiments at home and abroad,we conduct a comprehensive assessment on the experimental animal selection,model preparation,especially establishment and evaluation of ovalbumin-in-duced models,to help on the application and optimization about asthma models.%动物模型在支气管哮喘的研究中有很重要的价值。目前哮喘模型制备方法有多种，对模型的评价也无统一的规范化标准。该文通过检索分析近年来国内外有关哮喘动物实验的文献，从实验动物的选择、模型制备的方法，尤其是卵清蛋白造模的研究以及模型的评价等方面进行综合评估，以期有助于哮喘模型的应用和优化。