小潮气量和传统潮气量机械通气治疗小儿重症肺炎的疗效对比分析

摘要

Objective: To analyse the effects of low and conventional tidal volume mechanical ventilation on the treatment of children with severe pneumonia.Methods: 100 cases of children with severe pneumonia from June 2013 to June 2015 in our hospital were randomly divided into control group and observation group, each of 50 cases. hTe control group children with traditional tidal volume, tidal volume of 10~12 mL/kg; the observation group children using low tidal volume, tidal volume of 6~8 mL/kg, clinical parameters of two groups during treatmentwere analyzed.Results: hTe mechanical ventilation of the observation group was signiifcantly more than that of the control group (t=11.0770, P=0.0000), the mortality rate of observation group was signiifcantly higher than that of the control group (χ2=5.4825,P=0.0192). In the course of treatment, children mean airway pressure (Paw), fraction of inspiration O2 (FiO2), positive end expiratory pressure (PEEP), peak inflating pressure (PIP) and other clinical indexes of two groups had no significant difference (P>0.05), recurrent respiratory tract infections survival rate between the two groups had no significant difference (χ2=0.0624,P=0.8028). Conclusion: For children with severe pneumonia mechanical ventilation, the effect of traditional tidal volume shows better than low tidal volume.%目的：对比分析小潮气量和传统潮气量机械通气治疗小儿重症肺炎的疗效。方法：对2013年6月至2015年6月在我院进行接治的100例小儿重症肺炎进行研究，将患儿随机分为对照组和观察组，各50例，对照组的患儿采用传统潮气量，潮气量为10~12 mL/kg；观察组的患儿采用小潮气量，潮气量为6~8 mL/kg，对治疗过程中两组患儿临床参数的变化进行对比分析。结果：观察组患儿的机械通气时间明显多于对照组(t=11.0770，P=0.0000)，观察组患儿的病死率明显高于对照组(χ2=5.4825，P=0.0192)，治疗过程中，两组患儿的平均气道压(Paw)、吸入氧浓度(fraction of inspiration O2，FiO2)、高呼吸末正压(positive end expiratory pressure，PEEP)、吸气峰压(peak inflating pressure，PIP)等临床各指标的变化无明显差异(P>0.05)，观察组与对照组存活患儿的反复呼吸道感染发生率无明显差异(χ2=0.0624，P=0.8028)。结论：对重症肺炎患儿进行机械通气时，传统潮气量的治疗效果优于小潮气量。