POCT血糖仪与全自动生化分析仪检测血葡萄糖结果对比分析

摘要

Objective To discuss the difference and correlation between point of care testing(POCT) glucose meter and auto matic biochemical analyzer. Methods Control materials and patients samples with 5 gradual levels were detected continually for 5 days and then the coefficient of variation (CV) was calculated. Capillary blood glucose(CBG) of 54 diabetes patients were measured by POCT glucose meter,and venous plasma glucose(VPG) of the same patients were measured as well as by hexokinase method as control. The results were measured by SPSS13. 0,and the correlation between the two analyzers was evaluated. Results CV of the results of materials and patients samples with 5 gradual levels,detected by POCT,were 2. 6% - 4. 2% ,lower than the manufactur er s statement and in accordance with the required CV below 7. 5 % acclaimed by states. Abbott Optium Xceed POCT glucose meter had good correlations with automatic biochemical analyzer(r=0. 974). Conclusion The precision and accuracy of the POCT glucose meter were accorded with clinical requirements,and the results detected by POCT glucose meter could be closer to the plasma glu cose concentration. However,POCT glucose meter could be used for monitoring the fasting blood glucose and for the blood glucose screening test. POCT could not replace the traditional glucose tests and could not be used as diagnostic test.%目的 探讨POCT快速血糖仪与自动生化分析仪检测血糖结果的相关性及差异性,为临床提供参考.方法 用5个浓度的质控品和患者标本在POCT血糖仪上进行检测,连续测试5 d,计算变异系数(CV).用POCT快速血糖仪和全自动生化分析仪对54例患者的末梢血和静脉血浆进行血糖检测,测得的数据用SPSS统计学软件进行分析,评价POCT血糖仪与全自动生化仪与测定结果的相关性.结果 5个浓度的质控品和患者标本在POCT血糖仪上所测结果的CV在2.6%～4.2%,低于厂家的声明,也符合国家对血糖检测系统的测量重复性要求(CV不超过7.5%).雅培Optium Xceed血糖仪与全自动生化仪所测结果的相关系数(r)=0.974,相关性较好.结论 雅培Optium Xceed血糖仪在精密度和准确度等方面均符合临床要求,其检测结果接近血浆葡萄糖检测结果.但是POCT血糖仪仅可用于患者空腹血糖的监测或血糖过筛实验,不能代替实验室血糖的检测结果作为确诊实验.