亲属肾移植中供者年龄对移植肾功能的影响

摘要

目的 研究接受亲属高龄供肾者肾移植的患者近期移植肾功能状态,探讨高龄供肾者是否可保证移植肾的长期存活.方法选择接受父母供肾的肾移植患者86例,于近期观测肾功能指标.供者43~64岁,受者19~40岁.肾功能指标由血肌酐和尿素氮确定,由检验科提供.结果 86例肾移植患者中42例患者肾功能正常,其中24例患者接受的供者年龄大于或等于55岁,18例患者接受的供者年龄小于55岁.44例患者肾功能不正常,其中34例患者接受的供者年龄大于或等于55岁,10例患者接受的供者年龄小于55岁.接受供者年龄大于或等于55岁的患者与小于55岁的患者肾功能比较差异有统计学意义(P<0.05).结论 高龄供肾者不适宜作为肾移植的最佳供者,但亲属移植的患者移植肾功能下降后仍可维持较长时间肾功能.%Objective To study recent renal function in patients who received living renal from aged donors,to investigate the re nal security from aged donors. Methods Indicators of recent renal function were inspected in 86 patients,who received renal from father or mother. The age of donors and patients were 43-64 and 19 - 40 respectively. Serum creatine/urea nitrogen level,as the in dicators of renal function,was offered by clinical laboratory. Results In 86 recipients,42 patients renal function were normal,in which 24 patients received renal from donors equal with or more than 55 years old and 18 patients received renal from donors less than 55 years old. 44 patients renal function were abnormal,in which 34 patients received renal from donors equal with or more than 55 years old and 10 patients received renal from donors less than 55 years old. There was significant difference of renal function between recipients received from aged donor(more than or equal with 55 years old) and young donorQess than 55 years lod) (P< 0. 05). Conclusion It might be not the best choice to receive renal from aged donor, however, living renal transplant still could maintain long term renal function after decrease of renal function.