Objective To discuss the significance of rapid detection of alanine aminotransferase (ALT) before blood donation . Methods Dry chemistry method was performed for the screening of blood donors , and the results were compared with that of bio -chemical analyzer .Results In 7 500 specimens , the re-examination positive rate of ALT in screening group (5 000 cases) was 0 .1% , and that of non-screening group(2 500 cases) was 4 .75% , with significant difference between them (χ2=452 ,P<0 .05) . 22 samples were detected by the two methods at the same time , and the detection results were without statistical difference (P> 0 .05) .Conclusion Rapid detection of ALT in blood donors before blood donation could greatly reduce the unqualified rate of ALT in donated blood and save acquisition and test cost .%目的 探讨谷丙转氨酶的快速检测对献血者采血前进行初筛的意义.方法 采用干式化学法对献血者进行初筛,同时用生化分析仪复查检测结果并进行比较分析.结果 7 500例献血者中,初筛组(5 000例)采血后谷丙转氨酶复检阳性率为0.1%,未初筛组(2 500例)复检阳性率4.75%,两者差异有统计学意义(χ2=453,P<0.05).同时采用2种方法检测的22例标本,将其结果进行比较,两者差异无统计学意义(P>0.05).结论 对无偿献血者献血前采用快速检测谷丙转氨酶,可大大降低采血后谷丙转氨酶的不合格率,且节约检验成本.
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