Objective To investigate the infection status of Ureaplasma urealyticum (Uu) and its situation of drug resistance . Methods The separation ,identification and drug resistance test plate was used for Uu detection in 3 249 cases of cervical samples . Results The total infection rate of Uu was 47 .18% (1 533/3 249) .The patients with Uu infection mainly distributed in >20-40 years ,with the constituent ratio accounted to 90 .8% .The sensitive rates of Uu to josamycin and doxycycline were both higher than 95 .00% ,however ,the resistant rate of Uu to azithromycin and ofloxacin were both higher than 50 .00% .Conclusion The drug re‐sistant strains of Uu were common .The clinic should choose the sensitive antibiotics for the treatment according to the results of drug sensitivity test .%目的：探讨闽南地区女性解脲支原体（Uu）感染情况，并对其进行耐药分析。方法应用支原体分离、鉴定、药敏检测板对3249例宫颈拭子标本进行Uu检测。结果Uu总检出率为47．18％（1533/3249），Uu感染患者主要以大于20～40岁女性为主，占检出总例数的90．8％。Uu对交沙霉素、多西环素的敏感度都大于95．00％，而对阿奇霉素和氧氟沙星的耐药性均大于50．00％。结论Uu易出现耐药菌株，应根据药敏试验结果选择治疗药物。
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