不同透明角膜切口白内障超声乳化术后眼表和泪膜的变化

摘要

AIM:To study the changes of tear fiIm and ocuIar surface after cIear corneaI incision phacoemuIsification with different incision sizes. METHODS:Ninety patients (90 eyes) from May 2013 to May 2014 in our hospitaI were enroIIed. The patients were randomIy divided into two groups. Forty-five patients (45 eyes) in group A: coaxiaI 2. 2mm micro - incision phacoemuIsification cataract extraction and intraocuIar Iens(IOL) impIantation; forty-five patients (45 eyes) in group B: the conventionaI coaxiaI 3. 0mm smaII incision phacoemuIsification cataract extraction and IOL impIantation. The dry eye symptom ( DES) score, break up time ( BUT ) , Schirmer’s I test ( SIt ) and corneaI fIuorescein staining ( CFS ) score were assessed preoperativeIy and postoperativeIy. RESULTS: At 10, 20 and 30d postoperativeIy, the DES score in two groups increased, the DES score of group B was significantIy higher than those of group A and the differences were statisticaIIy significant ( t= -9. 501,-10. 070,-7. 961; aII P0. 05). The DES score, BUT, SIt and CFS score in group B showed statisticaIIy significant differences ( t=7. 321, 4. 071, 3. 620, 4. 214;aII P0.05)；B组患者的DES评分、BUT、SⅠt和CFS评分与术前相比差异明显,具有统计学意义( t=7.321、4.071、3.620、4.214,均P<0.05)。结论：白内障超声乳化术角膜切口大小对术后眼表和泪膜的变化具有一定的影响,切口小的能有效降低手术对患者眼表所造成的损伤,且术后早期对泪膜和眼表的影响比较小。