尿微量白蛋白和β2-微球蛋白在早期糖尿病肾病中的诊断价值

摘要

Objective: To investigate the diagnostic value of microalbuminuria (Malb) and β2-microglobulin (β2-MG） in nonage diabetic nephropathy. Method: The cases with diabetics were divided into A group and B group according to the course of disease, and the health cases were selected as the control group. The level of Malb and β2-MG were detected. Result: The level of BUN,Cr,Malb and β2-MG in the A and B groups were higher than those in the control group （ P＜0.05 ）. The level of BUN, Cr, MAIb and β2 -MG in the A group were higher than those in the B group ( P＜0.05 ). The level of Malb and β2-MG in the urine protein masccline groups were higher than those in the urine protein negative group (P＜0.05). Condusion: The diagnostic value of microalbuminuria（ Malb） and β2-microglobulin （ β2-MG )in nonage diabetic nephropathy is important, so they are worth being used.%目的:探讨尿微量白蛋白(Malb)和β2-微球蛋白(β2-MG)在诊断早期糖尿病肾病(DN)中的价值.方法:将我院糖尿病患者根据病程分为A组和B组,选择健康人群作为对照组,检测三组尿微量白蛋白和β2-微球蛋白等水平.结果:A、B组患者BUN、Cr、Malb及β2-MG均高于对照组(P＜0.05);A组BUN、Cr、Malb及β2-MG均高于B组(P＜0.05).尿蛋白阳性组Malb及β2-MG均高于阴性组 (P＜0.05).结论:尿微量白蛋白和β2-微球蛋白在诊断早期糖尿病肾病中的价值较大,值得应用.