Objective: To observe the application value of tumor markers of carbohydrate antigen 125 ( CA125 ) , carbohydrate antigen 19-9 ( CA19-9) and carcinoembryonic antigen (CEA) on diagnosis of senile benign and malignant ovarian tumors. Method:38 older patients with benign ovarian tumor treated in our hospital were selected as the group A, and 29 older patients with malignant tumor were chosen as the group B. 30 aged healthy patients were selected as the control group. Detecting the CA125,CA19-9 and CEA of 3 groups respectively. Result: According to statistical analysis, as for the positive rate of detection index, the group B was higher evidently than the group A and the control group, the group A was higher significantly than the control group. And the content of the group B was higher evidently than that of the group A and the control group. The index difference above between groups had significance (p<0.05 ). Conclusion: The positive rate of CA125、CA19-9 and CEA of elderly patients with malignant ovarian tumor is better evidently than that of elderly patients with benign tumor, which has high accuracy rate of diagnosis on ovarian tumors in the aged and has high clinical value.%目的:探讨肿瘤标志物糖类抗原125(CA125)、糖类抗原19-9(CA19-9)和癌胚抗原(CEA)在老年卵巢良恶性肿瘤诊断中的应用价值.方法:选取我院住院治疗的老年良性卵巢肿瘤患者38例,为A组,恶性肿瘤患者29例,为B组；另选取老年健康体检患者30例,为对照组；分别对三组患者进行CA125、CA19-9和CEA检测.结果:经检测三组患者检测指标阳性率经统计学分析,B组患者各指标检测结果阳性率均明显高于A组、对照组患者；A组患者各指标检测阳性率明显高于对照组:B组患者含量均明显高于A组和对照组,上述指标组间比较差异均具有显著性(P值均＜0.05).结论:老年卵巢恶性肿瘤患者CA125、CA19-9和CEA指标阳性率明显优于良性肿瘤患者,对老年卵巢肿瘤诊断准确率高,具有较高临床价值.
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