生活方式干预预防妊娠期糖尿病

摘要

Objective To understand the effect of lifestyle intervention in preventing gestational diabetes.Method 60 patients of gestational diabetes were divided into an experimental group (n=30) and a control group (n=30).The control group was treated with conventional insulin therapy while the experimental group was treated with lifestyle intervention in addition to the conventional insulin therapy.The glycemic control and pregnancy outcomes of the two groups were then compared.Findings Before the intervention, no significant difference was found between the two groups in the level of fasting plasma glucose ( FPG ) , 2 h postprandial blood glucose ( 2 HPG ) and glycosylated hemoglobin ( HbAlc ) ( P>0.05).After the intervention, significant difference was found between the two groups in the level of fasting plasma glucose (FPG), 2 h postprandial blood glucose (2 HPG) and glycosylated hemoglobin ( HbAlc) ( P <0.05).The rates of postpartum hemorrhage, premature rupture of membranes, and perinatal complications in the experimental group was significantly lower than those in the control group.The difference was statistically significant ( P <0.05) Conclusion Lifestyle intervention can effectively control the blood sugar level and reduce pregnant women and perinatal complications in patients with gestational diabetes.%目的：探讨生活方式干预对预防妊娠期糖尿病患者的作用。方法60例妊娠期糖尿病患者分为观察组与对照组各30例，对照组患者单纯给予常规胰岛素治疗，观察组患者另加以生活方式干预，观察两组患者的血糖控制及妊娠结局。结果干预前，两组患者空腹血糖、餐后2h血糖及糖化血红蛋白差异无统计学意义（P＞0．05）；干预后，两组患者上述指标均显著降低，且观察组降低更显著（ P＜0．05）。观察组患者合并妊高症、产后出血及胎膜早破等比例及围产儿并发症发生率均显著低于对照组（ P＜0．05）。结论生活方式干预能有效控制妊娠期糖尿病患者血糖水平，降低孕妇及围产儿并发症的发生。