代谢综合征各组分与高尿酸血症的相关性研究

摘要

Objective To understand the correlation of the components of metabolic syndrome (MS) to hyperuricemia. Method The data of 2288 subjects (all aged over 18 years) who were admitted for health examination were collected. Waist circumference(WC ),SBP,DBP,fasting plasma glucose ( FPG),TG,TC,HDL-c,LDL-c and UA were measured. Findings Logistic regression analysis suggested that WC and TG were positively correlated with hyperuricemia in men. WC, TG and LDL-c were positively correlated with hyperuricemia in women.Conclusion Serum uric acid intimately is more closely associated with abdominal obesity, dyslipidemia and the other metabolic syndrome components in women than in man.%目的：探讨代谢综合征（Metabolic Syndrome，MS）各组分腹型肥胖、血脂、血压、血糖与高尿酸血症（Hyperuricemia， HUA）的相关性。方法对2013年杭州四季青社区18岁以上的体检人群2288例进行调查，对该人群男女分别测定尿酸（UA）值及 MS 各组分的生化指标值。结果 logistic 回归分析显示，男性腰围（Waist Circumference，WC）、甘油三酯（Triglyceride，TG）与血 UA 水平升高呈显著正相关（P ＜0．05）；女性 WC、TG、低密度脂蛋白胆固醇（Low Den－sity Lipoprotein cholesterin ，LDL－c）与血 UA 水平升高呈显著正相关（P ＜0．05）。结论 HUA 与腹型肥胖及血脂异常密切相关，女性 HUA 还与 LDL－c 相关。