海南岛55岁及以上人群轻度认知障碍的患病率调查

摘要

Objective To investigate the prevalence of mild cognitive impairment (MCI) among 55-years old or over individuals in Hainan Island. Methods Demography, health history, mini-mental statue examination ( MMSE ), activity of daily living scale (ADR), clinic dementia rating scale (CDR) were used as screening tools.Results The prevalence of MCI was 4.25％ among the people who was 55 years old or over in Hainan island, in males and females were 3.88％, 4.57％, without significant difference, and increased with age(P ＜ 0.001 );in 55～64 years old and 65～74 year old groups, the prevalence of MCI in female was higher than that in male (P ＜ 0.05, P ＜0.01 ), but in 75～84 year old group, the prevalence of MCI in male was higher(P ＜ 0.05); in elder than or equal to 85 year old group, without significant difference; MCI prevalence was higher in people with lower educational level(P ＜0.001 ). Conclusion People with advance aged, with low education in Hainan Island are those at high risk of developing MCI, MCI should be prevented to reduce incidence of AD.%目的 全面了解海南岛55岁及以上人群轻度认知障碍(MCI)的患病率.方法 采用人口学、健康史、简易精神状态检查量表(MMSE)、日常生活自理能力量表(ADL)、临床痴呆评定量表(CDR)等问卷和量表进行筛查.结果 海南岛55岁及55岁以上人群MCI的患病率为4.25%,男性患病率为3.88%,女性患病率为4.57%,男女之间差异无统计学意义(P>0.05);各年龄组随着年龄的增加,患病率增高(P<0.001);相同年龄组男女之间比较,55～64岁、65～74岁年龄组女性患病率较男性高(P<0.05,P<0.01),75～84岁年龄组男性患病率较女性高(P<0.05),而在≥85岁的年龄组男女之间患病率差异无统计学意义(P>0.05).文化程度越低,患病率越高(P<0.001).结论 高龄、低教育水平是海南岛:MCI高发人群,应注意防治MCI,减少阿尔茨海默病(AD)的发生.