Objective Large scale study in mild cognitive impairement (MCI)in oldest-old people is scarce. In order to investigate Alzheimer's disease (AD), present study was design to explore the prevalence of MCI among oldest-old people in Shijiazhuang, China. Methods Chinese version of the Montreal Cognitive Assessment,Global Deterioration Scale,Activity of Daily Living,Hachinski Ischemic Scale and Hamilton Depression Scale were applied as screening tools. Prevalence of MCI among 1086 male veterans (aged 80 years old or older)from 28 military sanatorium in Shijiazhuang city were studied. Results The prevalence of MCI was 26.4% in oldest-old male veterans. With increase in educational background level, the prevalence of MCI was decreased (Y2=6.81,P=0.009). Conclusions The prevalence of MCI among oldest-old male veterans was increased significantly. Efforts should be put to monitor the MCI that developed in oldest-old people, whom are at high risk for AD. Also early intervention to treat MCI should be performed to slow down or stop progression of MCI into AD.%目的 目前国内对高龄轻度认知障碍(MCI)的大样本系统研究尚属少见.本研究系了解高龄MCI的流行现状,为进一步研究阿尔茨海默病(AD)提供依据.方法 于2010年8月对石家庄市28个部队干休所的1086例年龄≥82岁的男性高龄离退休干部进行MCI的患病率调查,采用中文版简易智能状态检查、蒙特利尔认知评估量表、总体衰退量表、日常生活能力量表(20项版本)及哈金斯基缺血指数量表、汉密尔抑郁量表为筛查工具.结果 高龄男性MCI的患病率为26.4％;随着受教育程度的提高,MCI患病率亦下降,差异有统计学意义(X2=6.81,P=0.009).结论 军队高龄离退休干部MCI患病率显著增高,应加强对军队高龄离退休干部MCI患者这一高危人群进行监测,早期进行干预治疗,从而延缓或阻止病情进展为AD.
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