Objective To investigate the cause of non-infectious urethral syndrome and to find appropriate treatment for it. Methods 117 adult female patients were divided into two groups by diagnostic criteria: non-infectious urethral syndrome group (group A, n=46) and urinary tract infection group (group B, n=71). All the patients were tested by Hamilton Depression Rating Scale for anxiety and depression before and after treatment The incidence of anxiety disorders, changes in anxiety scores before and after treatment, physical and mental anxiety score weights were compared between the two groups. Results The incidences of anxiety disorders of group A and group B were 84.78% and 7.04% respectively, showing statistically significant difference (P<0.01). No significant difference was found in the incidence of depression between the two groups (P＜0.05). HAMA scores of group A were (23.56±7.71) before treatment and (9.34±2.42) after treatment, with a significant statistical difference, while the score in group B showed no statistically significant difference before and after treatment (P<0.01). In group A, somatic anxiety scores were significantly higher than mental anxiety scores (P<0.01). Conclusion Female non-infectious urethral syndrome and anxiety disorders are closely related. Psychological intervention and/or anti-anxiety drug treatment are effective for them.%目的 探讨非感染性尿道综合征患者的病因,寻找合适的治疗方法.方法 分别对非感染性尿道综合征组(A组)和尿路感染组(B组)的成年女性患者治疗前后,采用汉米尔顿焦虑抑郁量表进行焦虑抑郁障碍检测,比较两组患者焦虑障碍的发生率、治疗前后焦虑评分的变化及非感染性尿道综合征组躯体、精神焦虑评分的权重.结果 A组、B组焦虑障碍的发生率分别为84.78％、7.04％,两组比较差异有显著的统计学意义(P＜0.01),而抑郁障碍两组比较差异无统计学意义((P＞0.05)；A组治疗前后HAMA评分分别为(23.56±7.71)分、(9.34±2.42)分,差异有统计学意义(P＜0.01),而B组治疗前后差异无统计学意义(P＞0.05)；A组躯体焦虑积分明显高于精神焦虑积分,存在显著的统计学意义(P＜0.01).结论 女性非感染性尿道综合征与焦虑障碍密切相关,心理干预和/或抗焦虑药物治疗有效.
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